Analysis Tools
skeleton
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• some areas of hypocellularity in the proliferative zone
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Allele Symbol Allele Name Allele ID |
Comp+ wild type MGI:2440658 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• some areas of hypocellularity in the proliferative zone
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• the apoptosis rates for chondrocytes in the growth plate, proliferative zone and resting zone are increased by 1.8-fold and 9.8-fold, respectively, relative to apoptosis rates in wild-type mice
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• proliferation of chondrocyte in the proliferative zone is decreased as indicated by a 12% reduction in bromodeoxyuridine-labelled chondrocytes relative to in wild-type mice
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• the apoptosis rates for chondrocytes in the growth plate, proliferative zone and resting zone are increased by 1.8-fold and 9.8-fold, respectively, relative to apoptosis rates in wild-type mice
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• proliferation of chondrocyte in the proliferative zone is decreased as indicated by a 12% reduction in bromodeoxyuridine-labelled chondrocytes relative to in wild-type mice
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• by 9 weeks male mice tibia are 2% shorter than in wild-type mice
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• the interterritorial matrix appears to contain less proteoglycan-like amorphous material than in wild-type mice making the collagen fibrils more prominent
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• mice exhibit mild pelvic deformation
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• by 9 weeks male mice tibia are 2% shorter than in wild-type mice
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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