All Phenotypes Plxnb2<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Plxnb2⁺
wild type
MGI:2440122

Summary

5 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Plxnb2^{tm1a(EUCOMM)Wtsi}/Plxnb2⁺	C57BL/6N-Plxnb2^{tm1a(EUCOMM)Wtsi}/Ieg	MGI:5782165
cx2	Plxnb2^tm1Matl/Plxnb2⁺ Sema4c^tm1Matl/Sema4c^tm1Matl	B6.129P2-Sema4c^tm1Matl Plxnb2^tm1Matl	MGI:4881697
cx3	Plxnb2^tm1Matl/Plxnb2⁺ Sema4g^tm1Kik/Sema4g^tm1Kik	B6.Cg-Plxnb2^tm1Matl Sema4g^tm1Kik	MGI:4881698
cx4	Plxnb1^tm1.1Ltam/Plxnb1⁺ Plxnb2^tm1Matl/Plxnb2⁺	involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6	MGI:5811331
cx5	Plxnb1^tm1.1Ltam/Plxnb1^tm1.1Ltam Plxnb2^tm1Matl/Plxnb2⁺	involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6	MGI:5811335

Allelic Composition	Plxnb2^{tm1a(EUCOMM)Wtsi}/Plxnb2⁺
Genetic Background	C57BL/6N-Plxnb2^{tm1a(EUCOMM)Wtsi}/Ieg
Cell Lines	EPD0051_2_D09

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plxnb2^{tm1a(EUCOMM)Wtsi} mutation (2 available); any Plxnb2 mutation (90 available)

Data Sources

IMPC Data for Plxnb2

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

increased body weight ( J:165965 )

IMPC - HMGU

renal/urinary system

abnormal urination ( J:165965 )

IMPC - HMGU

Allelic Composition	Plxnb2^tm1Matl/Plxnb2⁺ Sema4c^tm1Matl/Sema4c^tm1Matl
Genetic Background	B6.129P2-Sema4c^tm1Matl Plxnb2^tm1Matl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plxnb2^tm1Matl mutation (2 available); any Plxnb2 mutation (90 available)
Sema4c^tm1Matl mutation (0 available); any Sema4c mutation (36 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal cerebellar granule layer morphology ( J:167973 )

• mice exhibit a gap in the lobule X unlike wild-type mice and Sema4c^tm1Matl homozygotes

Allelic Composition	Plxnb2^tm1Matl/Plxnb2⁺ Sema4g^tm1Kik/Sema4g^tm1Kik
Genetic Background	B6.Cg-Plxnb2^tm1Matl Sema4g^tm1Kik

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plxnb2^tm1Matl mutation (2 available); any Plxnb2 mutation (90 available)
Sema4g^tm1Kik mutation (0 available); any Sema4g mutation (29 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:167973 )

N	• cerebellum morphology is normal

Allelic Composition	Plxnb1^tm1.1Ltam/Plxnb1⁺ Plxnb2^tm1Matl/Plxnb2⁺
Genetic Background	involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plxnb1^tm1.1Ltam mutation (2 available); any Plxnb1 mutation (106 available)
Plxnb2^tm1Matl mutation (2 available); any Plxnb2 mutation (90 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

mortality/aging ( J:168399 )

N	• mice are viable

reproductive system

reduced fertility ( J:168399 )

• mice are able to produce offspring although litters are very small

Allelic Composition	Plxnb1^tm1.1Ltam/Plxnb1^tm1.1Ltam Plxnb2^tm1Matl/Plxnb2⁺
Genetic Background	involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

mortality/aging ( J:168399 )

N	• mice are viable

reproductive system

reduced fertility ( J:168399 )

• mice are able to produce offspring although litters are very small

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