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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Robo2+
wild type
MGI:2439696
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Robo2em1(IMPC)Mbp/Robo2+ C57BL/6N-Robo2em1(IMPC)Mbp/MbpMmucd MGI:6408629
cx2
 		Robo2tm1.1Rilm/Robo2+
Tg(Hoxb7-EGFP)33Cos/? 		involves: 129 * C57BL/6 * CBA * FVB/N MGI:3759463


Genotype
MGI:6408629
ht1
Allelic
Composition		 Robo2em1(IMPC)Mbp/Robo2+
Genetic
Background		 C57BL/6N-Robo2em1(IMPC)Mbp/MbpMmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Robo2em1(IMPC)Mbp mutation (1 available); any Robo2 mutation (102 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
enlarged kidney ( J:211773 )
IMPC - UCD

renal/urinary system
enlarged kidney ( J:211773 )
IMPC - UCD

reproductive system
hydrometra ( J:211773 )
IMPC - UCD




Genotype
MGI:3759463
cx2
Allelic
Composition		 Robo2tm1.1Rilm/Robo2+
Tg(Hoxb7-EGFP)33Cos/?
Genetic
Background		 involves: 129 * C57BL/6 * CBA * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Robo2tm1.1Rilm mutation (0 available); any Robo2 mutation (102 available)
Tg(Hoxb7-EGFP)33Cos mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
abnormal renal/urinary system morphology ( J:125214 )
• mice exhibit unilateral congenital anomalies of the kidney and urinary tract with vesicouretal reflux (CAKUT-VUR)
• mice exhibit uretrovesical junctions
dilated ureter ( J:125214 )
• mice display early ureter dilation
large ureter ( J:125214 )
• mice exhibit massive and lesser megaureter




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory