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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Aprt+
wild type
MGI:2439065
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Aprtem1(IMPC)Hmgu/Aprt+ C57BL/6NCrl-Aprtem1(IMPC)Hmgu/Ieg MGI:7471868
ht2
 		Aprttm1Jat/Aprt+ involves: 129S2/SvPas * C57BL/6J MGI:5432779


Genotype
MGI:7471868
ht1
Allelic
Composition		 Aprtem1(IMPC)Hmgu/Aprt+
Genetic
Background		 C57BL/6NCrl-Aprtem1(IMPC)Hmgu/Ieg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aprtem1(IMPC)Hmgu mutation (1 available); any Aprt mutation (19 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism




Genotype
MGI:5432779
ht2
Allelic
Composition		 Aprttm1Jat/Aprt+
Genetic
Background		 involves: 129S2/SvPas * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aprttm1Jat mutation (2 available); any Aprt mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
nephrolithiasis ( J:103956 )
• some heterozygotes display crystalline material in the renal pelvis at autopsy
• a small amount of DHA crystal material is found in kidneys of both sexes, with no significant difference between male and female mice at 7-14 or at 30-45 days of age
• however, no renal pathological changes are observed at any age




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory