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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Apoa2+
wild type
MGI:2439059
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Apoa2tm1Bres/Apoa2+
Apoetm1Bres/Apoetm1Bres 		involves: 129P2/OlaHsd * 129S4/SvJae MGI:2655399


Genotype
MGI:2655399
cx1
Allelic
Composition		 Apoa2tm1Bres/Apoa2+
Apoetm1Bres/Apoetm1Bres
Genetic
Background		 involves: 129P2/OlaHsd * 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoa2tm1Bres mutation (5 available); any Apoa2 mutation (18 available)
Apoetm1Bres mutation (9 available); any Apoe mutation (164 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating cholesterol level ( J:37250 )
• 34% decrease in cholesterol levels compared to single Apoe homozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/24/2026
MGI 6.24 		The Jackson Laboratory