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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Sema4g+
wild type
MGI:2438270
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Sema4ctm1Matl/Sema4c+
Sema4gtm1Kik/Sema4g+
B6.Cg-Sema4ctm1Matl Sema4gtm1Kik MGI:4881700
cx2
Sema4ctm1Matl/Sema4ctm1Matl
Sema4gtm1Kik/Sema4g+
B6.Cg-Sema4ctm1Matl Sema4gtm1Kik MGI:4881701


Genotype
MGI:4881700
cx1
Allelic
Composition
Sema4ctm1Matl/Sema4c+
Sema4gtm1Kik/Sema4g+
Genetic
Background
B6.Cg-Sema4ctm1Matl Sema4gtm1Kik
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sema4ctm1Matl mutation (0 available); any Sema4c mutation (36 available)
Sema4gtm1Kik mutation (0 available); any Sema4g mutation (33 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• 40% of mice exhibit gaps in the granule layer of lobule II unlike wild-type mice
• 40% of mice exhibit ectopic granule cells in the molecular layer at subpilial positions unlike wild-type mice
• 69% of mice exhibit rostral lobules VIII and IX fusion unlike in wild-type mice




Genotype
MGI:4881701
cx2
Allelic
Composition
Sema4ctm1Matl/Sema4ctm1Matl
Sema4gtm1Kik/Sema4g+
Genetic
Background
B6.Cg-Sema4ctm1Matl Sema4gtm1Kik
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sema4ctm1Matl mutation (0 available); any Sema4c mutation (36 available)
Sema4gtm1Kik mutation (0 available); any Sema4g mutation (33 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• 60% of mice exhibit gaps in the granule layer of lobule II and X unlike wild-type mice
• 80% of mice exhibit ectopic granule cells in the molecular layer at subpilial positions unlike wild-type mice
• all mice exhibit rostral lobules VIII and IX fusion unlike in wild-type mice





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/04/2024
MGI 6.13
The Jackson Laboratory