Analysis Tools|
Allele Symbol Allele Name Allele ID |
Zeb2+ wild type MGI:2438052 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• do not develop aganglionic phenotypes phenotypes similar to patients with Mowat-Wilson Syndrome (Hirschsprung disease-mental retardation syndrome)
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Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| NOT | Mowat-Wilson syndrome | DOID:0060485 |
OMIM:235730 |
J:82084 |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• 14 of 16 exhibit maxillonasal clefts of varying severity, ranging from incomplete fusion of the maxillonasal processes to complete cleft of the processes
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• the spinal cord is dorsally open in the tail region
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• in the cerebrum, the shape of the ventricle is irregular, lined by a wavy ventricular zone
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• 8 of 16 exhibit exencephaly accompanied by the cerebrum defects
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• the spinal cord is dorsally open in the tail region
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• 14 of 16 exhibit maxillonasal clefts of varying severity, ranging from incomplete fusion of the maxillonasal processes to complete cleft of the processes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• 70% exhibit closure of the vaginal orifice
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/25/2025 MGI 6.24 |
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