All Phenotypes Flii<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Flii⁺
wild type
MGI:2437910

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Flii^{tm1b(KOMP)Mbp}/Flii⁺	C57BL/6N-Flii^{tm1b(KOMP)Mbp}/Ucd	MGI:5759235
ht2	Flii^tm1Hdc/Flii⁺	involves: BALB/cJ * C57BL/6	MGI:3796831

Allelic Composition	Flii^{tm1b(KOMP)Mbp}/Flii⁺
Genetic Background	C57BL/6N-Flii^{tm1b(KOMP)Mbp}/Ucd
Cell Lines	DEPD0005_10_F06

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Flii^{tm1b(KOMP)Mbp} mutation (1 available); any Flii mutation (60 available)

Data Sources

IMPC Data for Flii

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

renal/urinary system

abnormal kidney morphology ( J:211773 )

IMPC - UCD

Allelic Composition	Flii^tm1Hdc/Flii⁺
Genetic Background	involves: BALB/cJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Flii^tm1Hdc mutation (10 available); any Flii mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

enhanced wound healing ( J:119983 )

• 3 days after a 1 cm full-thickness incision was made in the dorsal skin, surface wound area measurements show smaller, more contracted wounds than in wild-type mice

• length of neoepidermis is significantly greater in mutant animals, and percentage or re-epithelialization of wounds is greater at 5 days after wounding

• by day 7, healing is comparable in mutants and wild-type

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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