All Phenotypes Scnm1<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Scnm1⁺
wild type
MGI:2437901

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Scn8a^med-J/Scn8a^med-J Scnm1^s/Scnm1⁺	involves: C3HeB/FeJ * C57BL/6J	MGI:6259406

Allelic Composition	Scn8a^med-J/Scn8a^med-J Scnm1^s/Scnm1⁺
Genetic Background	involves: C3HeB/FeJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scn8a^med-J mutation (2 available); any Scn8a mutation (98 available)
Scnm1^s mutation (0 available); any Scnm1 mutation (17 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

tremors ( J:108906 )

abnormal posture ( J:108906 )

• mice display dystonic postures

paraparesis ( J:108906 )

hearing/vestibular/ear

increased susceptibility to age-related hearing loss ( J:108906 )

impaired hearing ( J:108906 )

nervous system

abnormal action potential ( J:108906 )

• abnormal conduction of action potentials throughout the nervous system

abnormal CNS synaptic transmission ( J:108906 )

• absence of spontaneous bursting activity in the dorsal cochlear nucleus

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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