Analysis Tools|
Allele Symbol Allele Name Allele ID |
Rp1+ wild type MGI:2437881 |
| Summary |
3 genotypes |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• cone b-waves are reduced significantly at 4-8 months of age
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• saturating amplitude of the rod a-wave is reduced by 58% in 4-5 week old homozygotes and is practically absent at 4-8 months of age
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• maximum scoptic a-wave amplitudes are slightly reduced at 6 months of age
• flash sensitivity of rod photoreceptors is reduced about 50% at 3-4 weeks of age
• amplitudes of saturating responses are significantly decreased by 22%
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice at 6 months of age have OS abnormalities similar to Rp1l1tm1Jnz homozygotes
• 16% of mice have swirling discs in the OS compared to under 3% for controls
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• the a-wave amplitudes of 6 month old mice are similar to those in Rp1l1tm1Jnz homozygotes (i.e. 70% of normal)
• flash sensitivity of rod photoreceptors is reduced about 50% at 3-4 weeks of age
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• mice at 6 months of age have OS abnormalities similar to Rp1l1tm1Jnz homozygotes
• 16% of mice have swirling discs in the OS compared to under 3% for controls
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 01/28/2026 MGI 6.24 |
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