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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sema3f+
wild type
MGI:2437845
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Nrp2tm1.2Mom/Nrp2+
Sema3ftm1.2Ddg/Sema3f+ 		involves: 129P2/OlaHsd MGI:5897107
cx2
 		Sema3ftm1Mom/Sema3f+
Vmn1r49tm1Mom/Vmn1r49tm1Mom 		involves: 129P2/OlaHsd * C57BL/6J MGI:3760746


Genotype
MGI:5897107
cx1
Allelic
Composition		 Nrp2tm1.2Mom/Nrp2+
Sema3ftm1.2Ddg/Sema3f+
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nrp2tm1.2Mom mutation (1 available); any Nrp2 mutation (87 available)
Sema3ftm1.2Ddg mutation (0 available); any Sema3f mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal lymphatic vessel endothelial cell morphology ( J:226501 )
• increased numbers as much as in Sema3ftm1.2Ddg homozygotes




Genotype
MGI:3760746
cx2
Allelic
Composition		 Sema3ftm1Mom/Sema3f+
Vmn1r49tm1Mom/Vmn1r49tm1Mom
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sema3ftm1Mom mutation (1 available); any Sema3f mutation (40 available)
Vmn1r49tm1Mom mutation (1 available); any Vmn1r49 mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal accessory olfactory bulb morphology ( J:125485 )
• in 18.2% of mice, exhibit misprojections of V1rb2+ axons in the accessory olfactory bulb




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory