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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sema6a+
wild type
MGI:2437844
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Plxna4tm1Matl/Plxna4+
Sema6aGt(KST069)Byg/Sema6a+ 		involves: 129P2/OlaHsd MGI:5007634
cx2
 		Plxna2tm1Hfu/Plxna2+
Sema6aGt(KST069)Byg/Sema6a+ 		involves: 129P2/OlaHsd * C57BL/6 * CBA MGI:3795755


Genotype
MGI:5007634
cx1
Allelic
Composition		 Plxna4tm1Matl/Plxna4+
Sema6aGt(KST069)Byg/Sema6a+
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plxna4tm1Matl mutation (2 available); any Plxna4 mutation (102 available)
Sema6aGt(KST069)Byg mutation (1 available); any Sema6a mutation (84 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased sensory neuron number ( J:172268 )
• mice exhibit an increase in TH+ puncta in S4/S5 of the inner plexiform layer compared to in wild-type mice




Genotype
MGI:3795755
cx2
Allelic
Composition		 Plxna2tm1Hfu/Plxna2+
Sema6aGt(KST069)Byg/Sema6a+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plxna2tm1Hfu mutation (1 available); any Plxna2 mutation (128 available)
Sema6aGt(KST069)Byg mutation (1 available); any Sema6a mutation (84 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
ectopic cerebellar granule cells ( J:135408 )
• in the molecular layer




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory