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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Csf3+
wild type
MGI:2437834
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Csf3tm1Ard/Csf3+ involves: 129P2/OlaHsd * C57BL/6 MGI:2652727


Genotype
MGI:2652727
ht1
Allelic
Composition		 Csf3tm1Ard/Csf3+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Csf3tm1Ard mutation (2 available); any Csf3 mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased neutrophil cell number ( J:20400 )
• heterozygotes exhibit a chronic neutropenia, with blood neutrophil levels reduced to ~67% of wild-type levels, suggesting a gene-dosage effect

immune system
decreased neutrophil cell number ( J:20400 )
• heterozygotes exhibit a chronic neutropenia, with blood neutrophil levels reduced to ~67% of wild-type levels, suggesting a gene-dosage effect




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory