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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mocs2+
wild type
MGI:2437583
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Mocs2tm1b(EUCOMM)Wtsi/Mocs2+ C57BL/6N-Mocs2tm1b(EUCOMM)Wtsi/Ieg MGI:5757371
ht2
 		Mocs2tm1(KOMP)Vlcg/Mocs2+ involves: C57BL/6NTac MGI:5904779


Genotype
MGI:5757371
ht1
Allelic
Composition		 Mocs2tm1b(EUCOMM)Wtsi/Mocs2+
Genetic
Background		 C57BL/6N-Mocs2tm1b(EUCOMM)Wtsi/Ieg
Cell Lines EPD0560_5_C09
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mocs2tm1b(EUCOMM)Wtsi mutation (1 available); any Mocs2 mutation (26 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased body length ( J:211773 )
IMPC - HMGU

homeostasis/metabolism

vision/eye




Genotype
MGI:5904779
ht2
Allelic
Composition		 Mocs2tm1(KOMP)Vlcg/Mocs2+
Genetic
Background		 involves: C57BL/6NTac
Cell Lines 14669A-G7
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mocs2tm1(KOMP)Vlcg mutation (1 available); any Mocs2 mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
increased neuron apoptosis ( J:242197 )
• moderate neuronal apoptosis in the hippocampus, cortex and brainstem that is 5- to 6-fold lower than that observed in homozygotes

cellular
increased neuron apoptosis ( J:242197 )
• moderate neuronal apoptosis in the hippocampus, cortex and brainstem that is 5- to 6-fold lower than that observed in homozygotes




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory