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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nkd1+
wild type
MGI:2437028
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Nkd1tm1Kwha/Nkd1+ involves: 129S/SvEv MGI:3714500
ht2
 		Nkd1tm1Kwha/Nkd1+ involves: 129S/SvEv * C57BL/6 MGI:3714499
cx3
 		Nkd1tm1Kwha/Nkd1+
Nkd2tm1Kwha/Nkd2+ 		involves: 129S/SvEv * C57BL/6 MGI:3714515


Genotype
MGI:3714500
ht1
Allelic
Composition		 Nkd1tm1Kwha/Nkd1+
Genetic
Background		 involves: 129S/SvEv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nkd1tm1Kwha mutation (1 available); any Nkd1 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:122353 )
N
• mice are viable and fertile




Genotype
MGI:3714499
ht2
Allelic
Composition		 Nkd1tm1Kwha/Nkd1+
Genetic
Background		 involves: 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nkd1tm1Kwha mutation (1 available); any Nkd1 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:122353 )
N
• mice are viable and fertile




Genotype
MGI:3714515
cx3
Allelic
Composition		 Nkd1tm1Kwha/Nkd1+
Nkd2tm1Kwha/Nkd2+
Genetic
Background		 involves: 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nkd1tm1Kwha mutation (1 available); any Nkd1 mutation (15 available)
Nkd2tm1Kwha mutation (1 available); any Nkd2 mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
pup cannibalization ( J:122353 )
• significantly higher rate of cannabilization of offspring prior to weaning is observed in females having no or one wild-type copy of Nkd1 or Nkd2 (35% of 46 litters of females with one or no wild-type copies of either allele compared to only 14% of 51 litters of Nkd1-null or Nkd2-null homozygous females)




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory