Phenotypes associated with this allele

• Allele Symbol: Apcs⁺
• Allele Name: wild type
• Allele ID: MGI:2436899
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Apcs^tm1Mpe/Apcs^+	B6.Cg-Apcs^tm1Mpe	MGI:3775476

Genotype
MGI:3775476

ht1

• Allelic Composition: Apcs^tm1Mpe/Apcs⁺
• Genetic Background: B6.Cg-Apcs^tm1Mpe

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

abnormal spleen red pulp morphology ( J:90502 )

• mice exhibit red pulp lymphocytosis

abnormal spleen white pulp morphology ( J:90502 )

• mice exhibit coalescence of white pulp

increased spleen white pulp amount ( J:90502 )

increased autoantibody level ( J:90502 )

• intermediate increase with females more affected

glomerulonephritis ( J:90502 )

• mice, particularly females, exhibit intermediate frequency of proliferative, immune complex glomerulonephritis compared to wild-type mice

renal/urinary system

glomerulonephritis ( J:90502 )

• mice, particularly females, exhibit intermediate frequency of proliferative, immune complex glomerulonephritis compared to wild-type mice

renal glomerular immunoglobulin deposits ( J:90502 )

hematopoietic system

abnormal spleen red pulp morphology ( J:90502 )

• mice exhibit red pulp lymphocytosis

abnormal spleen white pulp morphology ( J:90502 )

• mice exhibit coalescence of white pulp

increased spleen white pulp amount ( J:90502 )