Phenotypes associated with this allele

• Allele Symbol: Phb1⁺
• Allele Name: wild type
• Allele ID: MGI:2436772
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Phb1^em1(IMPC)H/Phb1^+	C57BL/6NTac-Phb1^em1(IMPC)H/H	MGI:7472166
ht2	Phb1^Gt(XT0035)Wtsi/Phb1^+	involves: 129P2/OlaHsd * C57BL	MGI:3771855
ht3	Phb1^Gt(BGB069)Byg/Phb1^+	involves: 129P2/OlaHsd * C57BL	MGI:3771857

Genotype
MGI:7472166

ht1

• Allelic Composition: Phb1^em1(IMPC)H/Phb1⁺
• Genetic Background: C57BL/6NTac-Phb1^em1(IMPC)H/H

Data Sources

IMPC Data for Phb1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

decreased red blood cell distribution width ( J:211773 )

♂

IMPC - HAR

increased large unstained cell number ( J:211773 )

IMPC - HAR

homeostasis/metabolism

increased circulating triglyceride level ( J:211773 )

♂

IMPC - HAR

increased blood urea nitrogen level ( J:211773 )

♀

IMPC - HAR

immune system

increased large unstained cell number ( J:211773 )

IMPC - HAR

Genotype
MGI:3771855

ht2

• Allelic Composition: Phb1^{Gt(XT0035)Wtsi}/Phb1⁺
• Genetic Background: involves: 129P2/OlaHsd * C57BL

endocrine/exocrine glands

abnormal branching of the mammary ductal tree ( J:130064 )

♀ • upon hormone treatment to induce mammary gland ductal side branching and alveologenesis, mice produce more alveolar lateral budding and ductal side-branching, and a 1.96-fold increase in alveolar bud number per field compared to in wild-type mice

integument

abnormal branching of the mammary ductal tree ( J:130064 )

♀ • upon hormone treatment to induce mammary gland ductal side branching and alveologenesis, mice produce more alveolar lateral budding and ductal side-branching, and a 1.96-fold increase in alveolar bud number per field compared to in wild-type mice

Genotype
MGI:3771857

ht3

• Allelic Composition: Phb1^{Gt(BGB069)Byg}/Phb1⁺
• Genetic Background: involves: 129P2/OlaHsd * C57BL

endocrine/exocrine glands

abnormal branching of the mammary ductal tree ( J:130064 )

♀ • authors state that mice exhibit essentially the same phenotype as Phb^{Gt(XT0035)Wtsi}

integument

abnormal branching of the mammary ductal tree ( J:130064 )

♀ • authors state that mice exhibit essentially the same phenotype as Phb^{Gt(XT0035)Wtsi}