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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Mcm6+
wild type
MGI:2436677
Summary 9 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Mcm6Gt(YHD248)Byg/Mcm6+ involves: 129P2/OlaHsd * C3HeB/FeJ MGI:4838132
cx2
Mcm2Gt(AB0178)Wtsi/Mcm2+
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm6Gt(YHD248)Byg/Mcm6+
involves: 129P2/OlaHsd * C3HeB/FeJ MGI:4838123
cx3
Mcm2Gt(AB0178)Wtsi/Mcm2+
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm6Gt(YHD248)Byg/Mcm6+
Mcm7Gt(YTA285)Byg/Mcm7+
involves: 129P2/OlaHsd * C3HeB/FeJ MGI:4838124
cx4
Mcm2Gt(AB0178)Wtsi/Mcm2+
Mcm4Gt(RRE056)Byg/Mcm4+
Mcm6Gt(YHD248)Byg/Mcm6+
involves: 129P2/OlaHsd * C3HeB/FeJ MGI:4838125
cx5
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm4Gt(RRE056)Byg/Mcm4+
Mcm6Gt(YHD248)Byg/Mcm6+
involves: 129P2/OlaHsd * C3HeB/FeJ MGI:4838126
cx6
Mcm2Gt(AB0178)Wtsi/Mcm2+
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm4Gt(RRE056)Byg/Mcm4+
Mcm6Gt(YHD248)Byg/Mcm6+
involves: 129P2/OlaHsd * C3HeB/FeJ MGI:4838127
cx7
Mcm2Gt(AB0178)Wtsi/Mcm2+
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm4Gt(RRE056)Byg/Mcm4+
Mcm6Gt(YHD248)Byg/Mcm6+
Mcm7Gt(YTA285)Byg/Mcm7+
involves: 129P2/OlaHsd * C3HeB/FeJ MGI:4838137
cx8
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm4chaos3/Mcm4chaos3
Mcm6Gt(YHD248)Byg/Mcm6+
involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J MGI:4838114
cx9
Mcm4chaos3/Mcm4chaos3
Mcm6Gt(YHD248)Byg/Mcm6+
involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J MGI:4838116


Genotype
MGI:4838132
ht1
Allelic
Composition
Mcm6Gt(YHD248)Byg/Mcm6+
Genetic
Background
involves: 129P2/OlaHsd * C3HeB/FeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mcm6Gt(YHD248)Byg mutation (0 available); any Mcm6 mutation (38 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice

hematopoietic system
• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice




Genotype
MGI:4838123
cx2
Allelic
Composition
Mcm2Gt(AB0178)Wtsi/Mcm2+
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm6Gt(YHD248)Byg/Mcm6+
Genetic
Background
involves: 129P2/OlaHsd * C3HeB/FeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mcm2Gt(AB0178)Wtsi mutation (0 available); any Mcm2 mutation (53 available)
Mcm3Gt(RRR002)Byg mutation (0 available); any Mcm3 mutation (43 available)
Mcm6Gt(YHD248)Byg mutation (0 available); any Mcm6 mutation (38 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice

hematopoietic system
• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice




Genotype
MGI:4838124
cx3
Allelic
Composition
Mcm2Gt(AB0178)Wtsi/Mcm2+
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm6Gt(YHD248)Byg/Mcm6+
Mcm7Gt(YTA285)Byg/Mcm7+
Genetic
Background
involves: 129P2/OlaHsd * C3HeB/FeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mcm2Gt(AB0178)Wtsi mutation (0 available); any Mcm2 mutation (53 available)
Mcm3Gt(RRR002)Byg mutation (0 available); any Mcm3 mutation (43 available)
Mcm6Gt(YHD248)Byg mutation (0 available); any Mcm6 mutation (38 available)
Mcm7Gt(YTA285)Byg mutation (0 available); any Mcm7 mutation (45 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice

hematopoietic system
• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice




Genotype
MGI:4838125
cx4
Allelic
Composition
Mcm2Gt(AB0178)Wtsi/Mcm2+
Mcm4Gt(RRE056)Byg/Mcm4+
Mcm6Gt(YHD248)Byg/Mcm6+
Genetic
Background
involves: 129P2/OlaHsd * C3HeB/FeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mcm2Gt(AB0178)Wtsi mutation (0 available); any Mcm2 mutation (53 available)
Mcm4Gt(RRE056)Byg mutation (0 available); any Mcm4 mutation (43 available)
Mcm6Gt(YHD248)Byg mutation (0 available); any Mcm6 mutation (38 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice

hematopoietic system
• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice




Genotype
MGI:4838126
cx5
Allelic
Composition
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm4Gt(RRE056)Byg/Mcm4+
Mcm6Gt(YHD248)Byg/Mcm6+
Genetic
Background
involves: 129P2/OlaHsd * C3HeB/FeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mcm3Gt(RRR002)Byg mutation (0 available); any Mcm3 mutation (43 available)
Mcm4Gt(RRE056)Byg mutation (0 available); any Mcm4 mutation (43 available)
Mcm6Gt(YHD248)Byg mutation (0 available); any Mcm6 mutation (38 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice

hematopoietic system
• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice




Genotype
MGI:4838127
cx6
Allelic
Composition
Mcm2Gt(AB0178)Wtsi/Mcm2+
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm4Gt(RRE056)Byg/Mcm4+
Mcm6Gt(YHD248)Byg/Mcm6+
Genetic
Background
involves: 129P2/OlaHsd * C3HeB/FeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mcm2Gt(AB0178)Wtsi mutation (0 available); any Mcm2 mutation (53 available)
Mcm3Gt(RRR002)Byg mutation (0 available); any Mcm3 mutation (43 available)
Mcm4Gt(RRE056)Byg mutation (0 available); any Mcm4 mutation (43 available)
Mcm6Gt(YHD248)Byg mutation (0 available); any Mcm6 mutation (38 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice

hematopoietic system
• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice




Genotype
MGI:4838137
cx7
Allelic
Composition
Mcm2Gt(AB0178)Wtsi/Mcm2+
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm4Gt(RRE056)Byg/Mcm4+
Mcm6Gt(YHD248)Byg/Mcm6+
Mcm7Gt(YTA285)Byg/Mcm7+
Genetic
Background
involves: 129P2/OlaHsd * C3HeB/FeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mcm2Gt(AB0178)Wtsi mutation (0 available); any Mcm2 mutation (53 available)
Mcm3Gt(RRR002)Byg mutation (0 available); any Mcm3 mutation (43 available)
Mcm4Gt(RRE056)Byg mutation (0 available); any Mcm4 mutation (43 available)
Mcm6Gt(YHD248)Byg mutation (0 available); any Mcm6 mutation (38 available)
Mcm7Gt(YTA285)Byg mutation (0 available); any Mcm7 mutation (45 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice

hematopoietic system
• mice exhibit an increase in micronuclei containing red blood cells indicating increased genome instability compared with wild-type mice




Genotype
MGI:4838114
cx8
Allelic
Composition
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm4chaos3/Mcm4chaos3
Mcm6Gt(YHD248)Byg/Mcm6+
Genetic
Background
involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mcm3Gt(RRR002)Byg mutation (0 available); any Mcm3 mutation (43 available)
Mcm4chaos3 mutation (1 available); any Mcm4 mutation (43 available)
Mcm6Gt(YHD248)Byg mutation (0 available); any Mcm6 mutation (38 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• mortality observed in Mcm4chaos3/Mcm4chaos3 Mcm6Gt(YHD248)Byg/Mcm6+ mice is partially rescued

neoplasm
• tumor latency is shorted than in Mcm4chaos3 homozygotes




Genotype
MGI:4838116
cx9
Allelic
Composition
Mcm4chaos3/Mcm4chaos3
Mcm6Gt(YHD248)Byg/Mcm6+
Genetic
Background
involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mcm4chaos3 mutation (1 available); any Mcm4 mutation (43 available)
Mcm6Gt(YHD248)Byg mutation (0 available); any Mcm6 mutation (38 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• fewer than expected mice are produced
• only 10% of expected mice survive to birth

growth/size/body





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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory