Phenotypes associated with this allele

• Allele Symbol: Bicc1⁺
• Allele Name: wild type
• Allele ID: MGI:2436488
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Bicc1^em1(IMPC)Mbp/Bicc1^+	C57BL/6N-Bicc1^em1(IMPC)Mbp/MbpMmucd	MGI:6461106
ht2	Bicc1^jcpk/Bicc1^+	involves: 101 * C3H * T STOCK	MGI:3582953
cx3	Bicc1^jcpk/T(2;10)67Gso	involves: 101 * C3H * C3H/Rl * C57BL/6 * C57BL/RlGso * SEC/RlGso	MGI:3583140

Genotype
MGI:6461106

ht1

• Allelic Composition: Bicc1^em1(IMPC)Mbp/Bicc1⁺
• Genetic Background: C57BL/6N-Bicc1^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Bicc1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased locomotor activity ( J:211773 )

♀

IMPC - UCD

cardiovascular system

abnormal blood vessel morphology ( J:211773 )

♂

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♀

IMPC - UCD

small kidney ( J:211773 )

♀

IMPC - UCD

Genotype
MGI:3582953

ht2

• Allelic Composition: Bicc1^jcpk/Bicc1⁺
• Genetic Background: involves: 101 * C3H * T STOCK

renal/urinary system

kidney cyst ( J:23047 )

• 4 out of 17 heterozygotes between 10 and 15 months of age display cyctic abnormalities in the glomeruli

growth/size/body

kidney cyst ( J:23047 )

• 4 out of 17 heterozygotes between 10 and 15 months of age display cyctic abnormalities in the glomeruli

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
autosomal dominant polycystic kidney disease		DOID:898		J:23047

Genotype
MGI:3583140

cx3

• Allelic Composition: Bicc1^jcpk/T(2;10)67Gso
• Genetic Background: involves: 101 * C3H * C3H/Rl * C57BL/6 * C57BL/RlGso * SEC/RlGso

renal/urinary system

polycystic kidney ( J:75799 )

• polycystic kidneys seen by 10 days of age

enlarged kidney ( J:75799 )

growth/size/body

polycystic kidney ( J:75799 )

• polycystic kidneys seen by 10 days of age

distended abdomen ( J:75799 )

enlarged kidney ( J:75799 )