Phenotypes associated with this allele

• Allele Symbol: Fzd3⁺
• Allele Name: wild type
• Allele ID: MGI:2436015
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Fzd3^tm1b(EUCOMM)Hmgu/Fzd3^+	C57BL/6N-Fzd3^tm1b(EUCOMM)Hmgu/H	MGI:5757147
cx2	Fzd3^tm1Nat/Fzd3^+ Fzd6^tm1Nat/Fzd6^tm1Nat	involves: 129S1/Sv * 129X1/SvJ * C57BL/6	MGI:3652560

Genotype
MGI:5757147

ht1

• Allelic Composition: Fzd3^{tm1b(EUCOMM)Hmgu}/Fzd3⁺
• Genetic Background: C57BL/6N-Fzd3^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0675_6_G04

Data Sources

IMPC Data for Fzd3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased total body fat amount ( J:211773 )

♂

IMPC - HAR

behavior/neurological

decreased grip strength ( J:211773 )

♀

IMPC - HAR

homeostasis/metabolism

impaired glucose tolerance ( J:211773 )

♂

IMPC - HAR

skeleton

decreased bone mineral content ( J:211773 )

♂

IMPC - HAR

Genotype
MGI:3652560

cx2

• Allelic Composition: Fzd3^tm1Nat/Fzd3⁺; Fzd6^tm1Nat/Fzd6^tm1Nat
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

reproductive system

oligozoospermia ( J:105752 )

♂ • 10 fold reduction in sperm count

reduced male fertility ( J:105752 )

♂

cellular

oligozoospermia ( J:105752 )

♂ • 10 fold reduction in sperm count