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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Foxb1+
wild type
MGI:2435997
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Foxb1tm1Pgr/Foxb1+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3813478


Genotype
MGI:3813478
ht1
Allelic
Composition
Foxb1tm1Pgr/Foxb1+
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxb1tm1Pgr mutation (1 available); any Foxb1 mutation (17 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• at 3 weeks of age, heterozygotes display an intermediate phenotype in the posterior midbrain region relative to wild-type and homozygous mutant mice
• however, the heterozygous caudal hypothalamus remains unaffected and no alterations in the mammillary body are observed
• at 3 weeks of age, heterozygotes show an intermediate size reduction in the medial portion of inferior colliculi relative to wild-type and homozygous mutant mice
• however, the size of the most anterior cerebellar lobe, the lobulus culmen, remains unaffected





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory