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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ephb3+
wild type
MGI:2435808
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Efnb2tm1Henk/Efnb2+
Ephb2tm2Paw/Ephb2tm2Paw
Ephb3tm1Kln/Ephb3+ 		either: 129 or (involves: 129 * C57BL/6) or (involves: 129 * CD-1) MGI:3051580


Genotype
MGI:3051580
cx1
Allelic
Composition		 Efnb2tm1Henk/Efnb2+
Ephb2tm2Paw/Ephb2tm2Paw
Ephb3tm1Kln/Ephb3+
Genetic
Background		 either: 129 or (involves: 129 * C57BL/6) or (involves: 129 * CD-1)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Efnb2tm1Henk mutation (0 available); any Efnb2 mutation (27 available)
Ephb2tm2Paw mutation (0 available); any Ephb2 mutation (69 available)
Ephb3tm1Kln mutation (1 available); any Ephb3 mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
hypospadia ( J:91491 )
• an increased incidence of hypospadia compared to Efnb2tm1Henk heterozygotes is seen




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory