Phenotypes associated with this allele

• Allele Symbol: Cnbp⁺
• Allele Name: wild type
• Allele ID: MGI:2435782
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Cnbp^m1Hrb/Cnbp^+	B6.129S4-Cnbp^m1Hrb	MGI:3640665
ht2	Cnbp^tm1b(KOMP)Wtsi/Cnbp^+	B6N(Cg)-Cnbp^tm1b(KOMP)Wtsi/J	MGI:6480427

Genotype
MGI:3640665

ht1

• Allelic Composition: Cnbp^m1Hrb/Cnbp⁺
• Genetic Background: B6.129S4-Cnbp^m1Hrb

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, incomplete penetrance ( J:81582 )

• 40% of heterzygotes have multiple defects and die shortly after birth

growth/size/body

small mandible ( J:81582 )

• 40% of heterozygotes have small mandibles

decreased embryo size ( J:81582 )

• 40% of heterzygotes are smaller than wild-type littermates

craniofacial

small mandible ( J:81582 )

• 40% of heterozygotes have small mandibles

vision/eye

anophthalmia ( J:81582 )

• 40% of heterozygotes display a complete lack of eyes

skeleton

small mandible ( J:81582 )

• 40% of heterozygotes have small mandibles

embryo

decreased embryo size ( J:81582 )

• 40% of heterzygotes are smaller than wild-type littermates

Genotype
MGI:6480427

ht2

• Allelic Composition: Cnbp^{tm1b(KOMP)Wtsi}/Cnbp⁺
• Genetic Background: B6N(Cg)-Cnbp^{tm1b(KOMP)Wtsi}/J
• Cell Lines: EPD0357_3_G04

Data Sources

IMPC Data for Cnbp

homeostasis/metabolism

increased circulating potassium level ( J:211773 )

IMPC - JAX

decreased circulating serum albumin level ( J:211773 )

♂

IMPC - JAX

decreased blood urea nitrogen level ( J:211773 )

♂

IMPC - JAX

increased circulating chloride level ( J:211773 )

IMPC - JAX