All Phenotypes Taldo1<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Taldo1⁺
wild type
MGI:2435640

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Taldo1^tm1Perl/Taldo1⁺	involves: 129S6/SvEvTac * C57BL/6	MGI:3692523

Allelic Composition	Taldo1^tm1Perl/Taldo1⁺
Genetic Background	involves: 129S6/SvEvTac * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Taldo1^tm1Perl mutation (0 available); any Taldo1 mutation (15 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reduced male fertility ( J:114691 )

abnormal sperm physiology ( J:114691 )

• sperm cells show reduced mitochondrial transmembrane potential, diminished mitochondrial reactive oxygen intermediate production, reduced mitochondrial calcium levels, and reduced intracellular pH

impaired acrosome reaction ( J:114691 )

• acrosome reaction is reduced in sperm but to a smaller extent than in homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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