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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Septin4+
wild type
MGI:2435566
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Septin4tm1Hs/Septin4+ involves: 129/Sv * 129P2/OlaHsd * C57BL/6J MGI:3574663


Genotype
MGI:3574663
ht1
Allelic
Composition		 Septin4tm1Hs/Septin4+
Genetic
Background		 involves: 129/Sv * 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Septin4tm1Hs mutation (1 available); any Septin4 mutation (42 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
kinked sperm flagellum ( J:96669 )
• 20-30% of sperm showed an L-shaped morphology and a failure to straighten during their passage through the epididymis
• however, no sperm mitochondrial defects were observed and male fertility was not significantly reduced

cellular
kinked sperm flagellum ( J:96669 )
• 20-30% of sperm showed an L-shaped morphology and a failure to straighten during their passage through the epididymis
• however, no sperm mitochondrial defects were observed and male fertility was not significantly reduced




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/21/2024
MGI 6.23 		The Jackson Laboratory