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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fkbp5+
wild type
MGI:2435283
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Fkbp5tm1b(KOMP)Wtsi/Fkbp5+ C57BL/6N-Fkbp5tm1b(KOMP)Wtsi/MbpMmucd MGI:6461273
cx2
 		Fkbp4tm1Shou/Fkbp4tm1Shou
Fkbp5Gt(RRC236)Byg/Fkbp5+ 		involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 MGI:3710992


Genotype
MGI:6461273
ht1
Allelic
Composition		 Fkbp5tm1b(KOMP)Wtsi/Fkbp5+
Genetic
Background		 C57BL/6N-Fkbp5tm1b(KOMP)Wtsi/MbpMmucd
Cell Lines EPD0741_3_H03
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fkbp5tm1b(KOMP)Wtsi mutation (1 available); any Fkbp5 mutation (170 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
increased lean body mass ( J:211773 )
IMPC - UCD
increased kidney weight ( J:211773 )
IMPC - UCD

renal/urinary system




Genotype
MGI:3710992
cx2
Allelic
Composition		 Fkbp4tm1Shou/Fkbp4tm1Shou
Fkbp5Gt(RRC236)Byg/Fkbp5+
Genetic
Background		 involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fkbp4tm1Shou mutation (0 available); any Fkbp4 mutation (30 available)
Fkbp5Gt(RRC236)Byg mutation (0 available); any Fkbp5 mutation (170 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
hypospadia ( J:120960 )
• mice develop hypospadia similar to Fkbp4tm1Shou homozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory