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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Smarca2+
wild type
MGI:2435249
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Smarca2tm1Mya/Smarca2+ involves: 129S2/SvPas MGI:2661967
cn2
 		Smarca2tm1Mya/Smarca2+
Smarca4tm1.2Pcn/Smarca4tm1.1Pcn
Tg(Myh11-cre,-EGFP)2Mik/0 		involves: 129S2/SvPas * C57BL/6 * DBA/2 MGI:5009696


Genotype
MGI:2661967
ht1
Allelic
Composition		 Smarca2tm1Mya/Smarca2+
Genetic
Background		 involves: 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smarca2tm1Mya mutation (0 available); any Smarca2 mutation (91 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
increased body weight ( J:51536 )
• heterozygotes were of intermediate average weight between homozygous mutant and wild-type mice




Genotype
MGI:5009696
cn2
Allelic
Composition		 Smarca2tm1Mya/Smarca2+
Smarca4tm1.2Pcn/Smarca4tm1.1Pcn
Tg(Myh11-cre,-EGFP)2Mik/0
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smarca2tm1Mya mutation (0 available); any Smarca2 mutation (91 available)
Smarca4tm1.1Pcn mutation (0 available); any Smarca4 mutation (110 available)
Smarca4tm1.2Pcn mutation (1 available); any Smarca4 mutation (110 available)
Tg(Myh11-cre,-EGFP)2Mik mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
enlarged cecum ( J:172661 )
• by 4 weeks of age
decreased colon length ( J:172661 )
• the colon is shorter than in wild-type mice
megacolon ( J:172661 )
• by 4 weeks of age
abnormal small intestine morphology ( J:172661 )
• enlarged by 4 weeks of age
decreased small intestine length ( J:172661 )
• mice exhibit short smaller intestine




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory