Analysis Tools|
Allele Symbol Allele Name Allele ID |
Ager+ wild type MGI:2434471 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• depletion of conventional dendritic cells after treatment with diphtheria toxin is efficient with over 90% depletion
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• depletion is less effective than for conventional cells (about 50%)
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• depletion of conventional dendritic cells after treatment with diphtheria toxin is efficient with over 90% depletion
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• depletion is less effective than for conventional cells (about 50%)
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice show sustained hyperglycemia (and display diabetes)
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• glomerular cell number is decreased compared to Ager-sufficient transgenic controls at 4 and 8 months
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• progression of sclerosis is intermediate to Ager-sufficient or Ager-null transgenic mice
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/18/2025 MGI 6.24 |
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