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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pld2+
wild type
MGI:2434439
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Pld2tm1.1Gdp/Pld2+
Tg(APPSWE)2576Kha/0 		involves: 129X1/SvJ * C57BL/6 * SJL MGI:4880015


Genotype
MGI:4880015
cx1
Allelic
Composition		 Pld2tm1.1Gdp/Pld2+
Tg(APPSWE)2576Kha/0
Genetic
Background		 involves: 129X1/SvJ * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pld2tm1.1Gdp mutation (1 available); any Pld2 mutation (47 available)
Tg(APPSWE)2576Kha mutation (5 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:166741 )
N
• mice exhibit normal spatial working memory unlike Tg(APPSWE)2576Kha mice
enhanced contextual conditioning behavior ( J:166741 )
• compared to Tg(APPSWE)2576Kha mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory