All Phenotypes Gab1<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gab1⁺
wild type
MGI:2434157

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Gab1^tm1Wbm/Gab1⁺	involves: 129P2/OlaHsd * C57BL/6	MGI:3617775
cx2	Cd44^tm1Mak/Cd44^tm1Mak Gab1^tm1Wbm/Gab1⁺	involves: 129P2/OlaHsd * C57BL/6	MGI:4946522

Allelic Composition	Gab1^tm1Wbm/Gab1⁺
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gab1^tm1Wbm mutation (0 available); any Gab1 mutation (78 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:68751 )

• about 5% of heterozygotes develop after spasms 2-3 months of age and die

behavior/neurological

abnormal behavior ( J:68751 )

• about 5% of heterozygotes develop after spasms 2-3 months of age and die

Allelic Composition	Cd44^tm1Mak/Cd44^tm1Mak Gab1^tm1Wbm/Gab1⁺
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd44^tm1Mak mutation (1 available); any Cd44 mutation (73 available)
Gab1^tm1Wbm mutation (0 available); any Gab1 mutation (78 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

lethality, incomplete penetrance ( J:128984 )

• shortly after birth, 60% of the animals die

neonatal lethality, incomplete penetrance ( J:128984 )

• shortly after birth, 60% of the animals die

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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