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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Aurkb+
wild type
MGI:2433758
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Aurkbtm1.2Mama/Aurkb+ involves: 129/Sv * BALB/cJ * C57BL/6 * CD-1 * SJL MGI:5056442


Genotype
MGI:5056442
ht1
Allelic
Composition
Aurkbtm1.2Mama/Aurkb+
Genetic
Background
involves: 129/Sv * BALB/cJ * C57BL/6 * CD-1 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aurkbtm1.2Mama mutation (0 available); any Aurkb mutation (21 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• decreased life span due to an increase in spontaneous pathologies

reproductive system
• seen in some males by 12 months of age

neoplasm
• increase in pituitary adenocarcinomas

integument

liver/biliary system

cellular
• seen in some males by 12 months of age





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory