Phenotypes associated with this allele

• Allele Symbol: Efs⁺
• Allele Name: wild type
• Allele ID: MGI:2433550
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Efs^tm1Kale/Efs^+	either: (involves: 129X1/SvJ) or (involves: 129X1/SvJ * C57BL/6J)	MGI:3611471

Genotype
MGI:3611471

ht1

• Allelic Composition: Efs^tm1Kale/Efs⁺
• Genetic Background: either: (involves: 129X1/SvJ) or (involves: 129X1/SvJ * C57BL/6J)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

increased IgA level ( J:103757 )

• increase in IgA levels in response to NP-KLH immunization

increased IgG level ( J:103757 )

• increase in total IgG and IgG1 levels in response to NP-KLH immunization

increased inflammatory response ( J:103757 )

• exhibit enhanced effector immune response

small intestinal inflammation ( J:103757 )

• exhibit shortened, blunt villi, expanded laminae propriae, and enlarged crypts, indicating a lower level of inflammation than in homozygotes

digestive/alimentary system

small intestinal inflammation ( J:103757 )

• exhibit shortened, blunt villi, expanded laminae propriae, and enlarged crypts, indicating a lower level of inflammation than in homozygotes

hematopoietic system

increased IgA level ( J:103757 )

• increase in IgA levels in response to NP-KLH immunization

increased IgG level ( J:103757 )

• increase in total IgG and IgG1 levels in response to NP-KLH immunization