Phenotypes associated with this allele

• Allele Symbol: Pms2⁺
• Allele Name: wild type
• Allele ID: MGI:2433208
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Pms2^tm1Lisk/Pms2^+	involves: 129S2/SvPas	MGI:4820592

Genotype
MGI:4820592

ht1

• Allelic Composition: Pms2^tm1Lisk/Pms2⁺
• Genetic Background: involves: 129S2/SvPas

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased incidence of tumors by chemical induction ( J:61787 )

• N-methyl-N-nitrosourea (MNU)-treated mice exhibit a higher incidence and multiplicity of intestinal tumors (adenomas and adenocarcinomas) compared with similarly treated wild-type mice without loss of the wild-type allele

• however, the incidence of induced thymic lymphomas is normal

homeostasis/metabolism

increased incidence of tumors by chemical induction ( J:61787 )

• N-methyl-N-nitrosourea (MNU)-treated mice exhibit a higher incidence and multiplicity of intestinal tumors (adenomas and adenocarcinomas) compared with similarly treated wild-type mice without loss of the wild-type allele

• however, the incidence of induced thymic lymphomas is normal