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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Stat6+
wild type
MGI:2433144
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Stat6tm1Gru/Stat6+
Tg(Scgb1a1-Il13)2Eli/?
involves: 129S2/SvPas * C57BL/6 * CBA MGI:3832413


Genotype
MGI:3832413
cx1
Allelic
Composition
Stat6tm1Gru/Stat6+
Tg(Scgb1a1-Il13)2Eli/?
Genetic
Background
involves: 129S2/SvPas * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stat6tm1Gru mutation (4 available); any Stat6 mutation (54 available)
Tg(Scgb1a1-Il13)2Eli mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
respiratory system
• substantial epithelial fibrosis occurs
• discolored lungs
• distended lungs
• alveolar tissue destruction
• alveoli are enlarged
• develop airway hyper reactivity
• increased mucus production
• bronchoalveolar lavage contains increased numbers of macrophage, eosinophiles, lymphocytes, and neutrophiles

immune system
• bronchoalveolar lavage contains increased numbers of macrophage, eosinophiles, lymphocytes, and neutrophiles





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/13/2026
MGI 6.24
The Jackson Laboratory