Analysis Tools|
Allele Symbol Allele Name Allele ID |
E2f4+ wild type MGI:2433131 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• in all mice
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• at 3 weeks, efferent duct epithelium exhibit reduced multiciliated cells compared with control mice
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• in all mice
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• died by 18 months of age compared to 20-27 months in wild-type
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• developed pituitary tumors that were comparable to those arising in single heterozygous mutant Rb1 mice with respect to both incidence and size
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• developed thyroid tumors that were comparable to those arising in single heterozygous mutant Rb1 mice with respect to both incidence and size
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• developed pituitary tumors that were comparable to those arising in single heterozygous mutant Rb1 mice with respect to both incidence and size
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• developed thyroid tumors that were comparable to those arising in single heterozygous mutant Rb1 mice with respect to both incidence and size
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• developed pituitary tumors that were comparable to those arising in single heterozygous mutant Rb1 mice with respect to both incidence and size
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/18/2025 MGI 6.24 |
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