All Phenotypes Wnt5b<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Wnt5b⁺
wild type
MGI:2432385

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Wnt4^tm1Amc/Wnt4^tm1Amc Wnt5a^tm1Amc/Wnt5a^tm1Amc Wnt5b^tm1Tmj/Wnt5b⁺	involves: 129S1/Sv * 129S7/SvEvBrd	MGI:4412400

Allelic Composition	Wnt4^tm1Amc/Wnt4^tm1Amc Wnt5a^tm1Amc/Wnt5a^tm1Amc Wnt5b^tm1Tmj/Wnt5b⁺
Genetic Background	involves: 129S1/Sv * 129S7/SvEvBrd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wnt4^tm1Amc mutation (2 available); any Wnt4 mutation (23 available)
Wnt5a^tm1Amc mutation (1 available); any Wnt5a mutation (41 available)
Wnt5b^tm1Tmj mutation (0 available); any Wnt5b mutation (35 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal motor neuron morphology ( J:155074 )

• at E13.5, median motor column motor neurons at the thoracic level are decreased 67% compared to in wild-type mice

• at E13.5, hypaxial motor column motor neurons at the thoracic level are increased 39% compared to in wild-type mice

limbs/digits/tail

abnormal limb morphology ( J:155074 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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