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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Vpreb1b+
wild type
MGI:2432368
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Vpreb1atm1Ilm/Vpreb1atm1Ilm
Vpreb1btm1Ilm/Vpreb1b+
involves: 129P2/OlaHsd * C57BL/6 MGI:3843022


Genotype
MGI:3843022
cx1
Allelic
Composition
Vpreb1atm1Ilm/Vpreb1atm1Ilm
Vpreb1btm1Ilm/Vpreb1b+
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vpreb1atm1Ilm mutation (0 available); any Vpreb1a mutation (24 available)
Vpreb1btm1Ilm mutation (0 available); any Vpreb1b mutation (8 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• B220+ IgM+ cells reduced about 75%
• pre-BII cells reduced about 75%
• ratio of large to small pre-BII cells is normal
• pre-BI cell numbers are increased about 2 fold

hematopoietic system
• B220+ IgM+ cells reduced about 75%
• pre-BII cells reduced about 75%
• ratio of large to small pre-BII cells is normal
• pre-BI cell numbers are increased about 2 fold





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory