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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fgg+
wild type
MGI:2430658
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Fggtm1Lord/Fgg+ involves: 129P2/OlaHsd * C57BL/6 MGI:3771184


Genotype
MGI:3771184
ht1
Allelic
Composition		 Fggtm1Lord/Fgg+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fggtm1Lord mutation (0 available); any Fgg mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating fibrinogen level ( J:129828 )
• level of serum fibrinogen is one-half of normal
abnormal blood coagulation ( J:129828 )
• a small fraction of fibrinogen fails to clot upon addition of thrombin and instead remains soluble
abnormal thrombolysis ( J:129828 )
• calcium is only somewhat protective against plasmin degradation of fibrinogen

immune system
decreased circulating fibrinogen level ( J:129828 )
• level of serum fibrinogen is one-half of normal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/21/2024
MGI 6.23 		The Jackson Laboratory