Analysis Tools
hematopoietic system
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• thymocytes show a 50% reduction in frequency of apoptosis compared to wild-type littermates
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• 2-fold increase in frequency of apoptosis in spleen is detected
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• enlargement is more moderate compared to homozygotes
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• thymic weight is increased by 30% compared to wild-type littermates
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• slight reduction in frequency of CD44-expressing cells is observed, suggesting a deficit in memory T cell development
• a 50% reduction in cells memory cells (showing high CD44 expression) is observed in spleen, compared to controls
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immune system
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• thymocytes show a 50% reduction in frequency of apoptosis compared to wild-type littermates
|
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• 2-fold increase in frequency of apoptosis in spleen is detected
|
|
• enlargement is more moderate compared to homozygotes
|
|
• thymic weight is increased by 30% compared to wild-type littermates
|
|
• slight reduction in frequency of CD44-expressing cells is observed, suggesting a deficit in memory T cell development
• a 50% reduction in cells memory cells (showing high CD44 expression) is observed in spleen, compared to controls
|
cellular
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• thymocytes show a 50% reduction in frequency of apoptosis compared to wild-type littermates
|
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• 2-fold increase in frequency of apoptosis in spleen is detected
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endocrine/exocrine glands
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• thymocytes show a 50% reduction in frequency of apoptosis compared to wild-type littermates
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• enlargement is more moderate compared to homozygotes
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• thymic weight is increased by 30% compared to wild-type littermates
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