All Phenotypes Crem<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Crem⁺
wild type
MGI:2430291

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Crem^tm1Saco/Crem⁺	involves: 129/Sv * C57BL/6	MGI:3040663

Allelic Composition	Crem^tm1Saco/Crem⁺
Genetic Background	involves: 129/Sv * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crem^tm1Saco mutation (0 available); any Crem mutation (40 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

oligozoospermia ( J:31889 )

• seminal fluid from heterozygous males shows a 46% reduction in spermatozoa compared to wild-type males

teratozoospermia ( J:31889 )

• seminal fluid from heterozygous males shows a 35% decrease in the ratio of motile spermatozoa and a 2 fold increase in abnormal spermatozoa

reduced male fertility ( J:31889 )

• average litter size from heterozygous crosses is significantly smaller than heterozygous/homozygous crosses

cellular

oligozoospermia ( J:31889 )

• seminal fluid from heterozygous males shows a 46% reduction in spermatozoa compared to wild-type males

teratozoospermia ( J:31889 )

• seminal fluid from heterozygous males shows a 35% decrease in the ratio of motile spermatozoa and a 2 fold increase in abnormal spermatozoa

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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