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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cd5+
wild type
MGI:2430268
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Cd28tm1Mak/Cd28tm1Mak
Cd5tm1Cgn/Cd5+ 		either: (involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6) or (involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * DBA/1 * LP) MGI:3652975


Genotype
MGI:3652975
cx1
Allelic
Composition		 Cd28tm1Mak/Cd28tm1Mak
Cd5tm1Cgn/Cd5+
Genetic
Background		 either: (involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6) or (involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * DBA/1 * LP)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd28tm1Mak mutation (13 available); any Cd28 mutation (51 available)
Cd5tm1Cgn mutation (1 available); any Cd5 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal T cell clonal deletion ( J:110925 )
• mice show partial rescue of Vbeta11+CD4+ thymocytes from negative selection

hematopoietic system
abnormal T cell clonal deletion ( J:110925 )
• mice show partial rescue of Vbeta11+CD4+ thymocytes from negative selection




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory