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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Calb1+
wild type
MGI:2430218
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Calb1tm1Mpin/Calb1+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3686773
ht2
 		Calb1tm1.1(folA/cre)Hze/Calb1+ involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCr MGI:5522796


Genotype
MGI:3686773
ht1
Allelic
Composition		 Calb1tm1Mpin/Calb1+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Calb1tm1Mpin mutation (3 available); any Calb1 mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
ataxia ( J:38599 )
• 2-month old heterozygotes show significant deficits in initial trials in a thin horizontal rod test compared to controls but are significantly better than homozygotes; after first 2 sessions, no significant difference remains between mutant groups

nervous system
abnormal nervous system electrophysiology ( J:38599 )
• heterozygotes show a significant increase in dendritic calcium transients upon climbing fiber stimulation compared to controls




Genotype
MGI:5522796
ht2
Allelic
Composition		 Calb1tm1.1(folA/cre)Hze/Calb1+
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Calb1tm1.1(folA/cre)Hze mutation (1 available); any Calb1 mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:202879 )
• Heterozygous mice are viable and fertile with no gross physical or behavioral abnormalities.




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory