All Phenotypes Avpr2<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Avpr2⁺
wild type
MGI:2430052

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Avpr2^tm1Jwe/Avpr2⁺	involves: 129S1/Sv * 129X1/SvJ * CF-1	MGI:3047777

Allelic Composition	Avpr2^tm1Jwe/Avpr2⁺
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * CF-1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Avpr2^tm1Jwe mutation (0 available); any Avpr2 mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

polydipsia ( J:66094 )

• mice drank about two times more water than controls

homeostasis/metabolism

decreased urine osmolality ( J:66094 )

• urine hypoosmolality

renal/urinary system

decreased urine osmolality ( J:66094 )

• urine hypoosmolality

abnormal kidney physiology ( J:66094 )

• reduced urine concentrating ability

polyuria ( J:66094 )

• mice produced about three times more urine than controls

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
nephrogenic diabetes insipidus		DOID:12387		J:66094

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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