About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ccnb2tm1Thnt
targeted mutation 1, Tim Hunt
MGI:2429974
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ccnb2tm1Thnt/Ccnb2tm1Thnt involves: 129P2/OlaHsd * C57BL/6 MGI:2660700


Genotype
MGI:2660700
hm1
Allelic
Composition		 Ccnb2tm1Thnt/Ccnb2tm1Thnt
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccnb2tm1Thnt mutation (0 available); any Ccnb2 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, incomplete penetrance ( J:47430 )
• homozygous mutants are underrepresented in F2 progeny

growth/size/body
decreased body weight ( J:47430 )

reproductive system

hematopoietic system
small thymus ( J:47430 )
• thymus is somewhat smaller
increased double-negative T cell number ( J:47430 )
• slightly higher proportion of CD4-CD8 double-negative cells

immune system
small thymus ( J:47430 )
• thymus is somewhat smaller
increased double-negative T cell number ( J:47430 )
• slightly higher proportion of CD4-CD8 double-negative cells

endocrine/exocrine glands
small thymus ( J:47430 )
• thymus is somewhat smaller




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory