All Phenotypes Tg(Ttr-Cdkn1a)36Tvd MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Ttr-Cdkn1a)36Tvd
transgene insertion 36, Terry Van Dyke
MGI:2429747

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Ttr-Cdkn1a)36Tvd/?	B6.Cg-Tg(Ttr-Cdkn1a)36Tvd	MGI:5052061

Allelic Composition	Tg(Ttr-Cdkn1a)36Tvd/?
Genetic Background	B6.Cg-Tg(Ttr-Cdkn1a)36Tvd

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♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:94077 )

• mice develop diabetes and die between 2 to 4 months of age

homeostasis/metabolism

hyperglycemia ( J:94077 )

• mice develop diabetes and die between 2 to 4 months of age

liver/biliary system

decreased hepatocyte proliferation ( J:94077 )

abnormal oval cell morphology ( J:94077 )

• increased number of oval cells in liver

growth/size/body

decreased body size ( J:94077 )

cellular

decreased hepatocyte proliferation ( J:94077 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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