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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dab2tm1Xxx
targeted mutation 1, Xiang-Xi Xu
MGI:2429678
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dab2tm1Xxx/Dab2tm1Xxx involves: 129S6/SvEvTac * C57BL/6 MGI:2451360


Genotype
MGI:2451360
hm1
Allelic
Composition		 Dab2tm1Xxx/Dab2tm1Xxx
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dab2tm1Xxx mutation (0 available); any Dab2 mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:79862 )
• death occurs between E3.5 - E10.5

embryo
absent inner cell mass proliferation ( J:79862 )
• inner cell mass fails to proliferate and expand
abnormal egg cylinder morphology ( J:79862 )
• disorganization of embryonic cells at the egg cylinder stage

cellular
absent inner cell mass proliferation ( J:79862 )
• inner cell mass fails to proliferate and expand




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory