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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		M6prtm1Psa
targeted mutation 1, Paul Saftig
MGI:2429535
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		M6prtm1Psa/M6prtm1Psa involves: 129P2/OlaHsd * C57BL/6 MGI:3619606
hm2
 		M6prtm1Psa/M6prtm1Psa involves: 129P2/OlaHsd * C57BL/6J MGI:3581054


Genotype
MGI:3619606
hm1
Allelic
Composition		 M6prtm1Psa/M6prtm1Psa
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
M6prtm1Psa mutation (1 available); any M6pr mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal enzyme/coenzyme level ( J:106558 )
• beta-D-galactosidase, N-acetylglucosaminidase and alpha-D-mannosidase levels in spermatazoa show increases of 17, 63 and 51% respectively in homozygous mutants




Genotype
MGI:3581054
hm2
Allelic
Composition		 M6prtm1Psa/M6prtm1Psa
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
M6prtm1Psa mutation (1 available); any M6pr mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, incomplete penetrance ( J:16151 )
• fewer than expected homozygotes produced
• normal phenotype otherwise




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory