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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Msh2tm1Tts
targeted mutation 1, Teruhisa Tsuzuki
MGI:2389314
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Msh2tm1Tts/Msh2tm1Tts
Nudt1tm1Tts/Nudt1tm1Tts 		involves: 129S/SvEv * C57BL/6J MGI:3784584


Genotype
MGI:3784584
cx1
Allelic
Composition		 Msh2tm1Tts/Msh2tm1Tts
Nudt1tm1Tts/Nudt1tm1Tts
Genetic
Background		 involves: 129S/SvEv * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Msh2tm1Tts mutation (0 available); any Msh2 mutation (95 available)
Nudt1tm1Tts mutation (0 available); any Nudt1 mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal cell physiology ( J:79732 )
• spleen cells show a significant increase in frameshift mutations at mononucleotide runs relative to wild-type when assayed with a reporter system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory