All Phenotypes Msh2<tm1Tts> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Msh2^tm1Tts
targeted mutation 1, Teruhisa Tsuzuki
MGI:2389314

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Msh2^tm1Tts/Msh2^tm1Tts Nudt1^tm1Tts/Nudt1^tm1Tts	involves: 129S/SvEv * C57BL/6J	MGI:3784584

Allelic Composition	Msh2^tm1Tts/Msh2^tm1Tts Nudt1^tm1Tts/Nudt1^tm1Tts
Genetic Background	involves: 129S/SvEv * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Msh2^tm1Tts mutation (0 available); any Msh2 mutation (95 available)
Nudt1^tm1Tts mutation (0 available); any Nudt1 mutation (31 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

abnormal cell physiology ( J:79732 )

• spleen cells show a significant increase in frameshift mutations at mononucleotide runs relative to wild-type when assayed with a reporter system

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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