Analysis Tools
cardiovascular system
| N |
• both the left ventricular dP/dTmin and dP/dTmax are normal at baseline and respond normally to the beta-agonist isoproterenol
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Allele Symbol Allele Name Allele ID |
Tg(Myh6-ADRBK1)12Wjk transgene insertion 12, Walter Koch MGI:2389028 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• both the left ventricular dP/dTmin and dP/dTmax are normal at baseline and respond normally to the beta-agonist isoproterenol
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• there is a blunted response to rises in pressure induced by the beta-agonist isoproterenol
(J:37034)
• rises in pressure induced by the beta-agonist isoproterenol are depressed in these mice by about 20% at the highest dose
(J:127858)
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• heart rate failed to increase in response to the beta-agonist isoproterenol
• rises in pressure induced by the beta-agonist isoproterenol are depressed in these mice by about 20% at the highest dose
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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