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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Krt6a/Krt6btm1Der
targeted mutation 1, Dennis R Roop
MGI:2388396
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Krt6a/Krt6btm1Der/Krt6b+
Krt75tm1Der/Krt75+ 		involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6J MGI:3762628


Genotype
MGI:3762628
cx1
Allelic
Composition		 Krt6a/Krt6btm1Der/Krt6b+
Krt75tm1Der/Krt75+
Genetic
Background		 involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krt6a/Krt6btm1Der mutation (0 available); any Krt6b mutation (25 available)
Krt75tm1Der mutation (0 available); any Krt75 mutation (28 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
abnormal coat/ hair morphology ( J:127018 )
• authors state that the phenotypes observed are no more severe than those in Krt75tm1Der heterozygotes
abnormal nail morphology ( J:127018 )
• authors state that the phenotypes observed are no more severe than those in Krt75tm1Der heterozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory